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While traditional methods like protein precipitation, liquidliquid extraction, and solid-phase extraction (SPE) remain common, newer techniques (such as microextraction, microdialysis, and automated sample preparation) are gaining popularity due to their minimal sample loss, reduced matrix interference, and improved efficiency [40, 41]

10.1111/j.1528-1167.2006.00960.x Epilepsia 47 CuculloL.MarchiN.HossainM.JanigroD

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In addition, following TBI, a cascade of impaired oxidative respiration, increased production of reactive oxygen species, and inflammatory changes, similar to what is described above for neurodegenerative disease, results in additional neuronal injury [77]

These alterations not only extend its duration of action but also enable IGF-1 LR3 to circumvent binding with IGF-binding proteins, which typically impede the biological availability and efficacy of IGF-1

GSH vs GSSG Glutathione has two forms in the human body: reduced glutathione (GSH) and oxidized glutathione (GSSG)