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Nicorandil antiallodynic activity in a model of neuropathic pain is associated with the activation of ATP-dependent potassium channels and opioidergic pathways, and reduced production of cytokines and neutrophils recruitment in paw, sciatic nerve, and dorsal root ganglia

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Specifically, it is necessary to collect a sufficiently large specimen volume and to avoid exposure to bacteria from the surrounding environment, especially tap water, during collection

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