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Conversely, aerobic glycolysis, even in the presence of ample oxygen, involves the incomplete metabolism of glucose through the glycolytic pathway, providing both energy and metabolic intermediates like fructose-1,6-bisphosphate, pyruvate, and lactate for rapid tumor cell proliferation [63]

AD has a multifactorial origin, and one of the hallmarks of this disease involves the deposition of toxic senile plaques of amyloid- peptides in the brain

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Robertson AG, Kim J, Al-Ahmadie H, Bellmunt J, Guo G, Cherniack AD, et al