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however, the mechanisms for this imbalance have been unclear (22)

Int J Mol Med (2016) 38(1):33744

doi: 10.1007/s12011-019-1654-5 94

Liver diseases are serious diseases threatening the whole human health, mainly including metabolic associated fatty liver disease (MAFLD), alcoholic liver disease (ALD), chronic viral hepatitis (e.g., hepatitis B virus (HBV) and hepatitis C virus (HCV) infections), autoimmune hepatitis, hepatic schistosomiasis, drug-induced liver injury, liver cirrhosis (LC), hepatocellular carcinoma (HCC), and so on (Li, Q

Depletion of TrkB signalling in iSPNs impairs their inhibitory function, leading to spontaneous hyperactivity in Trkb Penk -KO mice with increasing age 13

But glutathione amino acid precursors mitigated this effect, making it more useful than standard antioxidants to protect skin against environmental pollutants