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There are three enzymes contributing to UPP: E1 (Ub-activating enzyme) and E2s (Ub-carrier) prepare Ub for conjugation, but the main enzyme in the process is the E3 (Ub-protein ligase) which transfers the activated ubiquitin to the protein substrate to be degraded [66]

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--------------- L-Glutathione Dikurangkan, Dikurangkan Glutathione adalah protein yang terdiri daripada asid amino L-sistein, asid L-glutamat, dan glisin

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MiRNA-124-3p.1 sensitizes hepatocellular carcinoma cells to sorafenib by regulating FOXO3a by targeting AKT2 and SIRT1