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CBD treatment effectively prevented paclitaxel-induced neuropathic pain and was associated with inhibition of type 4 Toll-like receptors (TLR4) and microglia activation [143]

Together, these pathways orchestrate mitochondrial biogenesis, synaptic remodeling, angiogenesis, anti-inflammatory responses, and metabolic reprogramming across multiple tissues

[PubMed] Yang X-L, Wu SM

2011 doi: 10.1172/JCI43144

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