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The adaptive immune system is in charge of your body's immune memory, which means it remembers how your body responded during a previous infection and inhibits it from occurring again

The mean change in body weight from baseline to week 104 was 15.2% in the semaglutide group ( n = 152) versus 2.6% with placebo ( n = 152), for an estimated treatment difference of 12.6 %-points (95% confidence interval, 15.3 to 9.8

This can lead to a painful condition called sciatica that tends to resolve on its own but can make you uncomfortable for several days or weeks

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