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Taddei S, Virdis A, Mattei P, Ghiadoni L, Gennari A, Fasolo CB et al
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vascular endothelial growth factor (VEGF) and angiopoietin-1, leading to the induction of genes involved in angiogenesis and thus represent therapeutic targets for the inhibition of tumor angiogenesis [122]
[1] Role in Treatment: ALC can be considered as first-line or adjunctive therapy for DPN
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In the phase II study, the MET positive subgroup of patients, as determined by IHC, had a prolonged mOS in the rilotumumab arm compared to the placebo arm [86]
