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doi: 10.1016/j.ghir.2009.09.005

Int Immunol 28(4):163171

Moving them to category 1 opens the door to more rigorous clinical trials, better safety data, and a deeper understanding of how these compounds work in the human body

Glutathione Peroxidase 4 Has a Major Role in Protecting Mitochondria from Oxidative Damage and Maintaining Oxidative Phosphorylation Complexes in Gut Epithelial Cells
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While results from in vitro studies suggest that vitamin B-12 may increase alpha-diversity and shift gut microbiome composition (beta-diversity), findings from animal studies and observational human studies were heterogeneous
