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Interestingly, when ISCU2 alone was silenced, increased amount of ISCU1 was observed in HeLa cells and vice versa, which led to the suggestion that these proteins may have redundant functions [107]

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Association between glutathione S-transferase T1 null genotype and risk of myelodysplastic syndromes: A comprehensive meta-analysis

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Myo-inositol improves developmental competence and reduces oxidative stress in Porcine parthenogenetic embryos

This suggests that the Pgp molecule spans the membrane twelve times