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10.1016/s0140-6736(21)01324-6 69 SaishoY

This pattern aligns with how chronic metabolic conditions like diabetes are managedwith continuous medication rather than temporary intervention

The problem is daunting: Powerful but expensive new drugs could help many of the 100 million American adults who have obesity and alleviate a grave public health concern

Market Expansion and Regulatory Evolution Regulatory bodies are becoming more aware that obesity is a long-term disease that needs medication treatment

This had been observed previously with very low-calorie diets outside of bariatric surgery (35), suggesting that caloric restriction at least partially, explains the acute improvement in glucose control after bariatric surgery (36, 37)
