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Beyond glucose control, GLP-1 receptor agonists improve insulin sensitivity, reduce systemic inflammation, and support cardiovascular health

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For instance, exenatide 10 g administered twice daily has a significantly higher probability of producing nausea compared to exenatide 5 g twice daily (OR: 2.28) and exenatide once-weekly formulations (OR: 2.78)

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These findings suggest that GLP-1R stimulation may exert differential effects depending on the neurobiological state associated with alcohol dependence [73]

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