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Roche reported positive Phase II topline data showing that its once-weekly dual glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptor agonist CT-388 achieved substantial, sustained, and dose-dependent weight loss through 48 weeks

Semaglutide is unlikely to cause liver damage and may even reduce liver fat, though it's not a treatment for liver conditions

These medications, primarily prescribed for type 2 diabetes and weight loss, are now at the center of thousands of claims alleging severe gastrointestinal injuries

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Lilly and other followers will need to generate their own evidence to support cardiovascular benefits of their own obesity treatments to compete on coverage and use
