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The First Wave: Older GLP-1 Medications Before semaglutide stole the spotlight, several other GLP-1 agonists were used primarily for diabetes management, with modest weight loss benefits

All medications are HSA/FSA eligible and available in all 50 states without insurance

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As semaglutide suppresses appetite and delays gastric emptying, patients do not feel an urge to eat frequently, which helps with weight loss and weight management

40 In the LIVE trial, which evaluated the effects of liraglutide on LV function in stable chronic HF patients with and without diabetes, at the end of treatment patients from the liraglutide group were able to walk 28 65 m longer during the 6MWT, compared with 3 89 m for patients in the placebo group, with a mean difference of 24 m

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