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The most commonly reported side effects of retatrutide in clinical trials are gastrointestinal, including nausea, vomiting, diarrhoea, constipation, and decreased appetite, consistent with other GLP-1-based therapies

and treat confirmed low testosterone serum levels according to guidelines, while acknowledging that whether TRT modifies GLP-1-associated lean mass trajectories remains unproven [6,19]
They act on receptors in the brain's hypothalamus and other areas involved in satiety signalling, leading to reduced hunger and increased feelings of fullness

[DOI] [PubMed] [Google Scholar] 488.Doyle M.E., Egan J.M
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13% for placebo, p = 0.08)
