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Description
Given that PKC and TRPM5 are downstream effectors of Gq signalling in beta cells, our next step involved determining whether the PKC inhibitor (calphostin C) and TRPM5 blocker (TPPO) suppress the triagonist-induced increase in GSIS
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Source: Drugwatch (pharmacist-reviewed)
Unlike oral tablets, which stomach acid destroys, patches avoid first-pass liver metabolism
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