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Reduction in Inflammation and Cardiovascular Risk: GLP-1 medications may: Reduce pro-inflammatory cytokines Improve microvascular function Positively influence the gut microbiome Support gut health and digestion Help balance hormones Emerging research suggests potential benefits for conditions such as: Rheumatoid arthritis Psoriasis Hormone Balance Polycystic ovarian syndrome (PCOS) These effects may help lower the risk of chronic diseases including heart disease, fatty liver disease, kidney disease, and autoimmune conditions

those receiving a non-GLP-1 drug

Therefore, GLP-1RAs hold promise as a novel therapeutic approach for diabetic patients with reduced -cell mass, stimulating -cell proliferation and differentiation ( FIGURE 3 4.4 Inhibition of -cell apoptosis Apoptosis plays an important role in the pathophysiology of diabetes

[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Garvey WT, Batterham RL, Bhatta M, Buscemi S, Christensen LN, Frias JP, et al

Better evidence on outcomes such as mortality could help clinicians determine not simply which drug produces the most weight loss, but which treatment offers the most appropriate balance for a particular patient
