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Despite the positive effects on weight gain, preconception RPM supplementation may have reduced subcutaneous fat deposition in the offspring, indicating a possible shift in energy partitioning toward lean tissue accretion (Heredia et al, 2025b)

Yes, they can be used together in some cases because they serve different purposes

Gut microbiota profiling of pediatric nonalcoholic fatty liver disease and obese patients unveiled by an integrated meta-omics-based approach

Even with the gold standard, there are questions as to what the degree of change (infiltration with inflammatory cells) exceeds normal wear-and-tear of day-to-day life

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doi: 10.1073/pnas.1534923100