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As your weight decreases over weeks and months, your anticoagulant requirements may need adjustment

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Wang P, Alvarez-Perez JC, Felsenfeld DP, et al

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This finding was confirmed and extended by a comprehensive metabolic phenotyping study, which showed that ablation of NTS PPG neurons did not affect meal patterns or energy expenditure in ad libitum feeding mice (Brierley et al., 2021)

A "technical issue" that results in the total loss of critical validation data is, by definition, a failure to exercise appropriate controls over the backup and retention of that data