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This resulted in the exclusion of one WT mouses data

One important consideration is that successful weight lossregardless of methodmay indirectly influence cortisol metabolism

This could help explain individual differences among humans in responsiveness to these drugs, including some well-known sex differences

et al., Nature Medicine (Vol 30, 2024, pp 20372048)

Interaction with diabetes medications in relation to ethnicity and dietary intake should be taken into account more rigorously in future studies