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Final considerations and new directions Despite of clinical evidence of increased incidence of bone diseases amongst smokers as well as worsening recovery in orthopedic surgeries, it is still unclear which pathological mechanisms are induced by CS and how these events impair bone turnover

It is now illegal for a retailer to sell any tobacco product including cigarettes, cigars and e-cigarettes to anyone under 21

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PLoS ONE, 8 (6), e66317