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Because thermoneutrality minimizes the contribution of non-shivering thermogenesis to whole-body energy expenditure and because non-shivering thermogenesis requires functional brown adipose tissue (BAT) [775], these data imply a contribution of endogenous GLP-1R signaling to the control of energy expenditure, at least in diet-induced obese mice, by regulating BAT activity

Wegovy, meanwhile, is a glucagon-like peptide-1 (GLP-1) receptor agonist licensed for chronic weight management in adults with obesity or overweight with weight-related comorbidities

Hyper-restrictive diets aren't necessary or recommendedGLP-1 naturally reduces appetite

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