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In a recent review, a small group of patients received the injections less frequently but still maintained weight loss and health benefits.

The studies involved subjects, rather small numbers in each case, who had diabetes, non-alcoholic fatty liver disease (NAFLD), polycystic ovary syndrome (PCOS), coronary disease or had kidney transplants

Primary care physicians often make decisions regarding the initiation of basal insulin in T2D, as they work closely with patients and are well placed to discuss and manage the transition to basal insulin therapy

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This review highlights key clinical considerations across reproductive stages, emphasizes the primacy of human exposure data where available, and identifies critical evidence gaps requiring future prospective study.

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