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Generally, those compounds are more harmful inhaled than digested, because some metabolic pathways of detoxification are absent in the human respiratory system [53]

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Thirdly, the adjustment for possible confounders was not carried out in these studies and, finally, the average amount smoked might have been higher compared with that in this study

In fact, there are many things you can do without cannabis that may improve your endocannabinoid tone (and, help with IBS symptoms!)