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Evidence indicates impaired vascular endothelial cells and angiogenesis inhibition in femoral head of patients with high-dose GC 7

Each stage of respiration, from glycolysis in the cytoplasm to the citric acid cycle and oxidative phosphorylation in mitochondria, depends on NAD+/NADH to carry reducing equivalents, thereby driving the production of cellular energy

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If circulation is limited, and the injury site is undernourished, cells cannot execute remodeling effectively

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