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Arch Toxicol 87(6):949968

The mechanisms that keep CpG islands free of methylation appear to involve binding of transcription factors and other transcriptional machinery or the act of transcription itself

gingivalis, as well as decreasing serum TNF- [62]

Finally, some chemotherapeutic agents and targeted agents, such as cisplatin and sorafenib, have previously been shown to be able to achieve antitumor effects by inducing ferroptosis (45,46)

Underscoring the importance of maintaining sufficient levels of retinal flavins in the retina, and the essential role of retbindin in that process, we found that ablation of Rtbdn resulted in significantly reduced levels of retinal flavins leading to retinal degeneration [15]

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