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BBR was delivered through dietary supplementation at 100 mg/kg/day

It was a population of older postmenopausal women, a meaningfully different biological context, in whom initiating hormone therapy may carry different risks than initiating it earlier [11]

There were no unexpected safety findings at the Phase 2 stage that would fundamentally alter the risk-benefit profile expected for this class

R.AlquierT.et al (2015)

Nutritional Priorities to Support GLP-1 Therapy for Obesity: A Joint Advisory From the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and the Obesity Society

Novel, in-vivo and in vitro data suggest that exenatide, a GLP-1 receptor agonist, may represent an ideal therapy for IIH through rapid reduction of CSF secretion at the choroid plexus, lowering ICP in addition to its weight loss properties