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Description
Farah C, Michel LYM, Balligand JL
Eur Heart J 2009;30(22):2769812
GLP-1 receptor agonists enhance insulin secretion by interacting with GLP-1 receptors in pancreatic beta cells
Results Baseline characteristics (GLP-1RAs vs SGLT2 inhibitors) A total of 4,591,936 individuals with NAFLD and type 2 diabetes were identified
Interestingly, disruption of the intrapancreatic infusion of Zn 2+ but not of Zn 2+ free insulin accelerates glucagon secretion in rats made diabetic by STZ, indicating that Zn 2+ but not insulin is the main stimulus underlying the Zn 2+ -insulin inhibition of glucagon secretion [595]
There was significant weight loss in both groups
