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Description
By influencing metabolic health and blood sugar regulation, they potentially support enhanced energy balance and body composition goals

Adults with overweight or obesity lost more weight with the GIP/GLP-1 dual agonist tirzepatide than the GLP-1 receptor agonist semaglutide, according to findings published in JAMA Internal Medicine

This is one reason GLP-1 therapy is best supervised rather than prescribed in isolation

Semaglutide GLP-1 not only enhances insulin signalling in the brain but, since GLP-1Rs are expressed in the brain [158], the former also seems to influence the control of synaptic plasticity, thus exerting neuroprotective effects [159, 160]

Childhood obesity and adult cardiovascular disease risk factors: a systematic review with meta-analysis

Evaluation by a licensed clinician is required for prescription medications, and prescription approval is not guaranteed
