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For instance, in aged high-fat diet-fed female mice with experimental HFpEF induced by angiotensin II infusion, liraglutide treatment (1 mg/kg once daily for 12 weeks) was shown to alleviate cardiac hypertrophy, atrial enlargement, and diastolic dysfunction, as evidenced by increased global longitudinal strain (Withaar et al

While acetazolamide is the standard medical therapy, weight loss is also considered a first-line treatment

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To help manage these side effects, follow the prescribed dose-escalation schedule exactly it's specifically designed to reduce GI effects

Critical nodes in signalling pathways: insights into insulin action

Deacon et al