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An overview of major safety and efficacy clinical trials is provided in Tables 1, 2, 3, and 4 to bring context to the mechanistic findings reported herein

[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Petersen MC, Vatner DF, and Shulman GI, Regulation of Hepatic Glucose Metabolism in Health and Disease, Nature Reviews

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[DOI] [PubMed] [Google Scholar] 129.Bakris GL, Agarwal R, Anker SD, Pitt B, Ruilope LM, Rossing P, et al

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Genetic and biased agonistmediated reductions in arrestin recruitment prolong cAMP signalling at glucagon family receptors