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Gastrointestinal side effects such as nausea, vomiting, and diarrhea are common with tirzepatide, particularly during dose escalation

Energy: unchanged or slightly reduced

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That said, complete dietary restriction is neither necessary nor sustainable for most patients

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For constipation: Increase fluid intake and dietary fiber gradually Consider over-the-counter osmotic laxatives like polyethylene glycol if recommended by your provider For diarrhea: Focus on hydration with electrolyte-containing fluids Over-the-counter loperamide may be appropriate for short-term use if approved by your provider Dose management strategies: If nausea is severe, discuss with your healthcare provider whether slowing the titration schedule is appropriate