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Conversely, abnormal blood glucose levels have been shown to elevate cancer risk and decrease survival rates in cancer patients [12, 50]
He did not have diabetes or thyroid disease

Novo Nordisk is the maker of Ozempic, Rybelsus and Wegovy
This is normal pharmacological tolerance, and it is one reason these medications use a dose escalation schedule rather than starting at the maximum
Glucagon-Like Peptide-1 (GLP-1): Effect on Kidney Hemodynamics and Renin-Angiotensin-Aldosterone System in Healthy Men

Those with severe kidney disease, active diabetic retinopathy, or recent pancreatitis require specialized evaluation before adding semaglutide