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The presence of diabetes accelerates the progression of MASLD

It is a medication most often prescribed for depression and smoking cessation, and FDA-approved for those indications

Eur Heart J 2006;27:23872393

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Acid contact time with the esophageal lining increases dramatically, raising the risk of esophagitis, stricture formation, and potentially Barrett esophagus with chronic exposure

Trial data shows it helped people reduce their weight by 13% over 13 weeks, just a percent or two below other popular obesity drugs but on a much shorter timeline