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1618 This, in turn, stimulates the transcription of genes for matrix-degrading enzymes such as metalloproteinase MMP 1 (collagenase), MMP-3 (stromelysin 1), and MMP-9 (92-kDa gelatinase)
The STEP 1 trial, for example, found that the average weight loss over 68 weeks was 14.9%
