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Endocrinology 154:127139

However, they have been found to have an unintended effect: steady, healthy weight loss through appetite suppression

These effects were accompanied by decreased GLP-1R plasma membrane diffusion under vehicle conditions, measured by Raster Image Correlation Spectroscopy (RICS) in rat insulinoma INS-1 832/3 cells with endogenous GLP-1R deleted [INS-1 832/3 GLP-1R KO cells (27)] stably expressing SNAP/FLAG-tagged human GLP-1R (SNAP/FLAG-hGLP-1R), an effect that is normally triggered by agonist binding (28), as also observed here (Supplementary Figure 1C, D)

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Depending on reconstitution concentration, that dose typically falls under 0.1 ml, well within this syringe capacity