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Weight regain has also been observed after bariatric procedures like gastric bypass, they noted, underscoring the challenge of long-term weight maintenance

A study published in the *International Journal of Pharmaceutics* found that peptide medications lose up to 30% potency within 36 months of expiration under standard storage conditions
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doi:10.1056/NEJMoa2206038 [5]4
Retatrutide activates three receptors at once (GIP, GLP-1, and glucagon), with the glucagon component adding increased calorie burning

There is an urgent need to develop effective treatments to address this global health issue
