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2.3 Signal analysis Disproportionality analysis, also known as case/non-case analysis, is widely used in pharmacovigilance for detecting drug-adverse reaction signals (Almenoff et al., 2007)

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The most frequently reported side effects during retatrutide initiation are gastrointestinal, including nausea, vomiting, diarrhoea, and abdominal discomfort

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This is because of how the SNAC technology temporarily changes the stomachs pH to allow for absorption

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