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The data that I will present on behalf of the OASIS 1 investigators are the first to describe the weight-lowering effect and safety of an oral GLP-1 analog (once-daily semaglutide 50 mg) in adults with overweight or obesity, without type 2 diabetes, and may, thus, guide the future treatment of obesity

Weeks 13-24: The Momentum Phase (12mg Maintenance Dose) Starting Weight Week 13: ~201 pounds | Expected Weight Week 24: 182-186 pounds | Net Loss This Period: 15-19 pounds | Total Loss: 34-38 pounds Whats Happening Physiologically Maximum dose of 12mg weekly maintains peak therapeutic effect

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That framing has shaped everything from treatment pathways to insurance coverage

This medication acts on three important hormone receptors

However, there are times when hiccups warrant a conversation with your healthcare provider