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Description
The main adverse effects leading to drug discontinuation were gastrointestinal disorders

Phase 3 data on long-term weight maintenance, cardiovascular outcomes, and safety across broader populations is not yet available

The Stark case series (2025) The most detailed clinical evidence comes from a case series published in the American Journal of Health-System Pharmacy by Stark et al

Noticing any discomfort

By indirectly lowering blood pressure, promoting weight loss and enhancing HbA1c control, GLP-1RAs minimise the risk of stroke [16]

