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They slow gastric emptying , reduce appetite signals in the brain, improve insulin sensitivity, and alter food reward pathways

At three years, the incidence was 1.40% vs

Tirzepatide is a glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved for type 2 diabetes management and chronic weight management

As illustrated in Figure 1, activation of the cAMP/PKA/CREB axis promotes the differentiation of white adipocytes into thermogenic-like adipocytes and enhances brown adipose tissue activity, contributing to lipid metabolism regulation and energy balance 8

Phentermine Phentermine is a clinician-guided appetite support option designed to help reduce hunger and support portion control as part of a medically supervised weight management plan

NICE recommends regular review of all diabetes medications to ensure they remain appropriate and effective, so discussing your treatment plan is an important part of ongoing diabetes care