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In the trials, patients stopped the medication and the support around it, full stop

Some people respond better to one drug or the other, but we dont know why

The company claims its semaglutide drops, which are applied under the tongue, contain the same active ingredient found in Ozempic and Wegovy and provide the powerful benefits of GLP-1 without injections. EllieMD further touts, under a benefits tab on the drops product page, that the drops offer prescription appetite suppression and are scientifically backed to help users lose weight, adding that the drops can help to lower blood sugar levels and potentially reduce the risk factors associated with conditions like type 2 diabetes, high blood pressure and cardiovascular disease, which are often linked to diabetes. Meanwhile, a recent EllieMD Instagram post boasts about the cardiovascular benefits of its GLP-1 medication, including decreased risk of cardiovascular disease, heart attack and stroke

For balance, a 2025 systematic review in Nephrology Dialysis Transplantation that pooled 12 trials with 36,568 participants found no significant overall increase in acute kidney injury (relative risk 0.94)

Abell TL, Kuo B, Esfandyari T, et al

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