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While the precise mechanisms of GIP remain incompletely understood in humans, it contributes to energy balance not only by enhancing glucose-dependent insulin secretion but also by modulating adipose tissue metabolism, appetite, and energy expenditure (14)

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Is the reason that you're seeing the mental health improvements [with youth on anti-obesity drugs] because society just has such contempt for fat people? Shashoua asked

While there have been concerns over the drug leading to suicidal ideation, a preliminary FDA evaluation released in January 2024 failed to find evidence that Ozempic caused suicidal thoughts or tendencies

Obesity wars: molecular progress confronts an expanding epidemic

The role of hypothalamic estrogen receptors in metabolic regulation