glp 1 drugs vs metformin Ozempic for Weight Loss: Similarities and Differences Clinical Focus on GLP-1 Agonists
Description
JAMA Pediatr 178 , 1307-1315 (2024)

Enhances glucose-dependent insulin secretion from pancreatic -cells 2

doi: 10.1016/s0091-3057(97)90017-4

The ACC also supports the use of GLP-1R agonists for cardiovascular risk reduction in patients with T2DM and multiple ASCVD risk factors, independent of glucose control or background antihyperglycemic therapy [122]

The path to weight loss is also guided by hormones, metabolism, and genetics
The pancreas produces less insulin over time, and a single medicine that worked well at diagnosis often stops being enough after a few years
