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Su, X., Federoff, H

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The study found that Ex-4 significantly reduced both the mRNA and protein expression of the pro-inflammatory cytokines IL-2, IL-17a, IFN, and TNF in IELs activated by immobilized anti-CD3 and soluble anti-CD28 antibodies

Patients should be counseled about these risks and monitored appropriately if concurrent use is pursued
Few semaglutidetreated participants (4.3%) permanently discontinued treatment for GI AEs
Tappenden KA, Edelman J, Joelsson B