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While clinical vigilance cannot be overstated, clinical decisions should be individualized, with particular emphasis on careful management of established NAION risk factors in patients treated with semaglutide

Potential downsides include temporary GI symptoms (nausea, constipation), cost/coverage variability, and the possibility of weight regain if old habits return after stopping

Liposomes as a Technically Mature Delivery Platform Among the delivery systems under investigation, liposomal encapsulation stands out for its technical maturity and pharmaceutical relevance

Ozempic is a brand-name insulin-pen product

After using ChatGPT, the authors reviewed and edited the content as needed and take full responsibility for the content of the publication

NICE guidance on obesity management (NG246) emphasises multicomponent interventions including dietary modification, increased physical activity, and behavioural strategies