glp 1 for migraines GLP-1 Meds Chronic Migraine: Research, Benefits, and Side Effects — Migraine Again Chronic Pain and Migraines being
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Patients should report persistent stool changes to their GP, particularly if accompanied by abdominal pain, as GLP-1 therapy carries rare risks of pancreatitis and gallbladder disease
Plus, real-world adherence data from Blue Health Intelligence and a 2025 study in JAMA Network Open show that roughly 30 percent of patients discontinue within the first month and over half quit within three months with physical discomfort cited as a primary driver. However, with the exception of nausea, Carroll explains that what often tips a patient toward wanting to discontinue the medication isnt one severe symptom
The FDA Adverse Event Reporting System shows a likely link between GLP-1 RAs (specifically liraglutide) and increased risk of pancreatitis
