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Further analyses revealed that cotadutide 300 g improved lipid profiles, liver enzyme levels (AST and ALT), and markers of liver fibrosis, including propeptide of type III collagen, and fibrosis-4 index, compared to placebo

Ultimately, care must be utilized in selecting patients with appropriate medical history, and regular monitoring of side effects is paramount

Again, why

They are generally well-tolerated, with a favorable safety profile in long-term use

Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, et al

Any off-label use should be approached cautiously, ideally within clinical trials, and discussed thoroughly with healthcare providers