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The 2016 LEADER (NCT01179048) trial was the first to demonstrate a modest cardiovascular benefit in patients with T2D and stable cardiovascular disease receiving liraglutide, when compared to placebo

The wave of weight-loss drugs being prescribed to patients across the country may be behind a new era in obesity treatment

Research in mice lacking HO-1 has revealed the overall function of HO-1 in restoring functional macrophages, maintaining iron balance within tissues, and increasing tolerance to oxidative stress conditions [98,99,100]

The goal is improving long-term health, not simply achieving short-term weight loss

Hypoglycemia and hyperglycemia are both predictors for adverse outcomes in hospitalized patients

Most studies indicate that these medications must be taken long term, as weight is easily regained once treatment stops