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Stopping GLP-1 receptor agonists 14 days prior to total hip or knee arthroplasty may reduce several key risk factors associated with anesthesia complications, according to results presented here.“Specifically for semaglutide, stopping that medication 14 days before surgery is safest based upon the dataset that we have to minimize your risks with anesthesia, especially when

This infographic breaks down these drugs by active ingredients, brand names and approved uses of popular GLP-1s.

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Both glucagon-like peptide-1 receptor agonists (GLP-1RA) and sodium-glucose cotransporter-2 (SGLT-2) inhibitors can reduce CV risk in patients with T2D, and both are recommended by the American Diabetes Association to reduce the risk of major cardiovascular events (MACE)

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In a letter, the FDA said it needs more data to fully understand several possible risks tied to the drug, including heart and liver problems.